JACC:糖尿病会明显影响房颤患者预后!

2017-09-06 MedSci MedSci原创

糖尿病是房颤患者发生血栓栓塞的风险因素,然而,糖尿病对房颤患者预后结局的影响尚未阐明。近日,在国际心血管权威杂志JACC上发表了一篇旨在评估比较伴有或不伴有糖尿病的房颤患者的临床特征、健康状态和预后差异的临床研究。本研究纳入了ORBIT-AF注册数据库中的9749名房颤患者,终点事件包括患者的临床特征、健康状态、房颤治疗管理、2年死亡率、住院率、血栓栓塞事件、心衰和房颤进展。最终结果表明,伴有糖尿

糖尿病房颤患者发生血栓栓塞的风险因素,然而,糖尿病房颤患者预后结局的影响尚未阐明。近日,在国际心血管权威杂志JACC上发表了一篇旨在评估比较伴有或不伴有糖尿病的房颤患者的临床特征、健康状态和预后差异的临床研究。

本研究纳入了ORBIT-AF注册数据库中的9749名房颤患者,终点事件包括患者的临床特征、健康状态、房颤治疗管理、2年死亡率、住院率、血栓栓塞事件、心衰和房颤进展。最终结果表明,伴有糖尿病的患者(29.5%)更年轻,更容易出现高血压、慢性肾脏疾病、心衰、冠心病和卒中。与不伴有糖尿病的患者相比,伴有糖尿病的房颤患者的房颤对生活质量影响的评分更低(80 vs 82.4),并且接受抗凝治疗的可能性更大(p<0.001)。糖尿病与死亡率增高呈相关性,包括全因死亡率和心血管源性死亡率。此外,糖尿病房颤患者的非心源性死亡、心源性猝死和住院率均有所升高,但在血栓栓塞事件、出血相关住院率、新发心衰和房颤进展方面无明显差异。

研究结果显示,糖尿病可影响房颤患者的预后,包括增加死亡和住院风险,降低患者的生活质量。

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    2018-08-14 hbwxf
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