J Rheumatol:美国类风湿性关节炎—间质性肺病的流行病学调查

2018-12-07 xiangting MedSci原创

RA-ILD的患病率随时间而升高。RA-ILD与存活率下降有关。

间质性肺病(ILD)通常与类风湿性关节炎(RA)相关,并具有较高的发病率和死亡率。本研究目的是计算美国RA相关性ILD(RA-ILD)的患病率、发病率、医疗保健费用和死亡率。

这项回顾性队列分析使用2003年至2014年Truven 医疗市场监测商业和医疗补充健康保险数据库以及社会安全管理死亡数据库。根据医疗索赔上的诊断选择RA-ILD患者。结局是1年患病率和一般登记人群中RA-ILD的发病率、全因和呼吸相关医疗保健费用(按照2014年美元标准),以及新诊断患者亚组的全因存活率。采用描述性分析。没有进行统计学检验。

10年间,RA-ILD的患病率范围为每10万人3.2-6.0例,发病率范围为每10万人2.7-3.8例。750例偶发性患者有5年的随访数据。在此期间,72%的患者入院,76%有急诊就诊经历。平均5年总费用为每位患者173,405美元(SD 158,837美元)。第1年和第5年的患者年度费用最高。首次诊断后5年,35.9%的患者存活。

RA-ILD的患病率随时间而升高。对于能够随访5年的患者,医疗资源的使用和花费随时间保持稳定,但数额很大。RA-ILD与存活率下降有关。

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    2019-10-26 amy0559
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    2018-12-09 lmm397
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    2018-12-09 xugumin
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