Intens Care Med:术中心跳骤停后的靶向温度管理!

2017-04-07 xing.T MedSci原创

在IOCA后使用了TTM的患者不到三分之一。TTM与这种患者的感染相关,但与出血或冠状动脉事件无关。TTM不能独立预测IOCA后1年良好的功能结局。

术中心脏骤停(IOCA)后体温管理的研究数据较少。近日,危重病医学领域权威杂志Intensive Care Medicine上发表了一篇研究文章,研究人员旨在描述靶向温度管理(TTM)(32-34°C)方式、不良事件以及IOCA患者1年功能结局。

研究人员对在2008年至2013年期间IOCA后入住ICU的患者进行了回顾性研究,该研究的主要结局指标为1年功能指标。

在101名患者中[35名女性和66名男性;平均年龄为62岁(四分位距为42-72)],68名(67.3%)患者为ASA PS I至III,有57名(56.4%)患者接受了急诊手术。首次记录的节律为心脏停顿有44名(43.6%)患者,无脉性电活动有36名(35.6%)患者,以及室颤/心动过速有20名(19.8%)患者。从心脏骤停到心肺复苏和恢复自主循环(ROSC)的平均时间分别为0min(0-0)和10min(4-20)。30名(29.7%)接受了TTM治疗的患者感染风险增加(P=0.005),但没有心律失常、出血或代谢、电解质紊乱。通过多变量分析,ROSC之前一次或多次除颤与1年良好的功能结局相关(比值比为3.06,95%可信区间为1.05-8.95,P=0.04),并且急诊外科手术与1年良好的功能结局相关(比值比为0.36;95%可信区间为0.14-0.95,P=0.038)。TTM使用与1年良好的功能结局并不独立相关(比值比为0.82;95%可信区间为0.27-2.46,P=0.72)。

在IOCA后使用了TTM的患者不到三分之一。TTM与这种患者的感染相关,但与出血或冠状动脉事件无关。TTM不能独立预测IOCA后1年良好的功能结局。

原始出处:

Anne-Laure Constant, et al. Targeted temperature management after intraoperative cardiac arrest: a multicenter retrospective study.Intensive Care Medicine.2017. http://icmjournal.esicm.org/journals/abstract.html?v=43&j=134&i=4&a=4709_10.1007_s00134-017-4709-0&doi=

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    2017-04-08 飛歌

    学习了很有用

    0