Chest:雾霾与烟雾下的生存:**干预可行否?

2017-07-13 MedSci MedSci原创

目前,尽管地区政府机构在不断努力,但是,空气污染仍然是全球公共卫生的重大威胁。2017年1月,伦敦出现了类似于1960年发生的伦敦雾的严重烟雾爆发事件。中国的雾霾也在北京出现,其中PM2.5(特别是小于2.5微米)的水平甚至高达500微克/立方米。欧洲地区烟雾和中国地区的阴霾每年都导致大量的过早死亡,其发生率分别为40万和120万,其中主要是由于呼吸系统疾病、脑血管疾病和缺血性心脏病。除了空气污染

目前,尽管地区政府机构在不断努力,但是,空气污染仍然是全球公共卫生的重大威胁。


2017年1月,伦敦出现了类似于1960年发生的伦敦雾的严重烟雾爆发事件。

中国的雾霾也在北京出现,其中PM2.5(特别是小于2.5微米)的水平甚至高达500微克/立方米。
欧洲地区烟雾和中国地区的阴霾每年都导致大量的过早死亡,其发生率分别为40万和120万,其中主要是由于呼吸系统疾病、脑血管疾病和缺血性心脏病。

除了空气污染以外,还有一些其他的有害环境因素,如二手烟。对于中国、印度、美国和俄罗斯这些吸烟者人数众多的国家来说,烟雾的熏烟是一个严重的问题。

随着新型基因组学和表观遗传学的研究发展,已经揭示了空气污染和吸烟引起的突变特征和肺癌等疾病的表观遗传学编辑,目前,也已经开发出了准确的干预策略,用于对特异性突变和/或表观遗传引发的疾病引起的早期干预。此外,也可以开发由基因-药物相互作用和基因组生物标志物引导的新疗法。

目前迫切需求讨论如何管理雾霾和烟雾对全球人类健康的毒性影响,以及对不可避免的暴露于雾霾和二手烟的精确干预。

原始出处:
Cai HL, Wang C. Survival with Smog and Smoke: Precision Intervention? Chest. 2017 Jul 7. pii: S0012-3692(17)31206-0. doi: 10.1016/j.chest.2017.06.030. 

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    2018-02-20 Smile2680
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    2017-07-15 chenshujs
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    2017-07-13 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

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