CHEST:OSA或重叠综合征患者接受择期非心脏手术应首先识别高碳酸血症

2016-01-21 fsy 译 MedSci原创

在OSA患者中,伴有肥胖低通气综合征(OHS)患者比只患有OSA的患者会发生较多的合并症。OHS可能会造成择期非心脏手术(NCS)后的术后并发症的风险较高,通常在手术时是无法识别的。本研究的目的是回顾性识别OHS患者,并与那些只患有OSA的患者比较他们的手术后的结果。在一个大型队列OSA得患者符合OHS标准的患者在一家大型三级医疗中心接受择期NCS。研究人员确定了OSA和OHS以及OHS的临床决定

在阻塞性睡眠呼吸暂停(OSA)患者中,伴有肥胖低通气综合征(OHS)患者比只患有OSA的患者会发生较多的合并症。OHS可能会造成择期非心脏手术(NCS)后的术后并发症的风险较高,并且通常无法在手术时识别。本研究的目的是回顾性识别OHS患者,并与那些只患有OSA的患者比较他们的手术后的结果。

在一个大型队列中,OSA患者以及符合OHS标准的患者在一家大型三级医疗中心接受择期NCS。研究人员确定了OSA和OHS以及OHS的临床决定因素(BMI、呼吸暂停低通气指数[AHI])引起的术后效果。多变量逻辑和线性回归模型分别用于二分法分析持续的结果。

与OSA患者相比,有高碳酸血症的确诊或可能的OHS和重叠综合征患者更有可能患有术后呼吸衰竭(OR,10.9;95%Cl,3.7-32.3;P<0.0001),术后心脏衰竭(OR,5.4;95%Cl,1.9-15.7; P=0.002),长时间插管(OR,3.1;95%CI,0.6-15.3; P=0.2),术后ICU转移(OR,10.9;95%CI,3.7-32.3; P<0.0001),和更长的ICU(β系数为0.86;SE,0.32; P=0.009)和住院时间(β系数,2.94; SE,0.87; P =0.0008)。在OHS的临床决定因素中,在单变量或多变量回归分析中,无论是BMI还是AHI,都与任何术后结果相关。

该研究结果强调了在接受择期非心脏手术时OSA或重叠综合征患者需要术前识别高碳酸血症。

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    2016-11-11 Smile2680
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Jan 27 18:33:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59968, encodeId=386f59968c5, content=这篇文章有一定深度, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Tue Jan 26 17:18:00 CST 2016, time=2016-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59969, encodeId=51d359969ac, content=是一篇不错的文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Tue Jan 26 17:18:00 CST 2016, time=2016-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349745, encodeId=abb31349e45f1, content=<a href='/topic/show?id=3d0d134904c' target=_blank style='color:#2F92EE;'>#OSA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13490, encryptionId=3d0d134904c, topicName=OSA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430578, encodeId=7ba914305e85e, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488263, encodeId=6a111488263ef, content=<a href='/topic/show?id=f37799413a6' target=_blank style='color:#2F92EE;'>#非心脏手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99413, encryptionId=f37799413a6, topicName=非心脏手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585979, encodeId=02e515859e9fb, content=<a href='/topic/show?id=30e110253124' target=_blank style='color:#2F92EE;'>#高碳酸血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102531, encryptionId=30e110253124, topicName=高碳酸血症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aff417344311, createdName=lvygwyt2787, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=)]
    2016-01-27 李继凯

    有深度

    0

  5. 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href='/topic/show?id=3d0d134904c' target=_blank style='color:#2F92EE;'>#OSA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13490, encryptionId=3d0d134904c, topicName=OSA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430578, encodeId=7ba914305e85e, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488263, encodeId=6a111488263ef, content=<a href='/topic/show?id=f37799413a6' target=_blank style='color:#2F92EE;'>#非心脏手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99413, encryptionId=f37799413a6, topicName=非心脏手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585979, encodeId=02e515859e9fb, content=<a href='/topic/show?id=30e110253124' target=_blank style='color:#2F92EE;'>#高碳酸血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102531, encryptionId=30e110253124, topicName=高碳酸血症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aff417344311, createdName=lvygwyt2787, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=)]
    2016-01-26 doctording1

    这篇文章有一定深度

    0

  6. 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href='/topic/show?id=3d0d134904c' target=_blank style='color:#2F92EE;'>#OSA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13490, encryptionId=3d0d134904c, topicName=OSA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430578, encodeId=7ba914305e85e, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488263, encodeId=6a111488263ef, content=<a href='/topic/show?id=f37799413a6' target=_blank style='color:#2F92EE;'>#非心脏手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99413, encryptionId=f37799413a6, topicName=非心脏手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585979, encodeId=02e515859e9fb, content=<a href='/topic/show?id=30e110253124' target=_blank style='color:#2F92EE;'>#高碳酸血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102531, encryptionId=30e110253124, topicName=高碳酸血症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aff417344311, createdName=lvygwyt2787, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=)]
    2016-01-26 doctording1

    是一篇不错的文章

    0

  7. 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href='/topic/show?id=3d0d134904c' target=_blank style='color:#2F92EE;'>#OSA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13490, encryptionId=3d0d134904c, topicName=OSA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430578, encodeId=7ba914305e85e, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488263, encodeId=6a111488263ef, content=<a href='/topic/show?id=f37799413a6' target=_blank style='color:#2F92EE;'>#非心脏手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99413, encryptionId=f37799413a6, topicName=非心脏手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1585979, encodeId=02e515859e9fb, content=<a href='/topic/show?id=30e110253124' target=_blank style='color:#2F92EE;'>#高碳酸血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102531, encryptionId=30e110253124, topicName=高碳酸血症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aff417344311, createdName=lvygwyt2787, createdTime=Sat Jan 23 12:56:00 CST 2016, time=2016-01-23, status=1, ipAttribution=)]
    2016-01-23 bioon3
  8. 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