Sci Rep:一种常见的抗氧化剂就可延缓皮肤衰老

2017-06-01 tulip1999 来宝网

对许多人来说,随着年龄增长,皮肤健康状况越来越差是最让人讨厌的一件事情。随着我们年龄日益增长,我们的皮肤逐渐失去弹性,变薄变干,修复能力下降。然而,一项最新研究发现了一种抗氧化剂能够延缓皮肤衰老。



对许多人来说,随着年龄增长,皮肤健康状况越来越差是最让人讨厌的一件事情。随着我们年龄日益增长,我们的皮肤逐渐失去弹性,变薄变干,修复能力下降。然而,一项最新研究发现了一种抗氧化剂能够延缓皮肤衰老

研究人员揭示了一种叫做亚甲蓝的化合物,能够减缓人类皮肤细胞以及人体皮肤3D 模型的衰老征象。

该项研究的首席作者,科利奇帕克马里兰大学(UMD)细胞生物学与分子遗传学助理研究教授Zheng-Mei Xiong及其同事说道,他们的研究结果表明,可将亚甲蓝添加到化妆品中来帮助对抗皮肤衰老。

研究人员在《科学报告》杂志上报道了他们的最新研究成果。

亚甲蓝是主要用于治疗高铁血红蛋白症的一种化合物。

然而,最新研究表明,亚甲蓝能够有效地减缓细胞衰老——也就是说,能够阻止细胞分裂,而这被认为是细胞衰老过程中的一个关键因素。

作者写道:“基于以上观察,我们推测MB(亚甲蓝)或许能够有效地保护皮肤免受氧化应激,延缓皮肤衰老。”

为了验证他们的推测,Xiong及其同事对亚甲基蓝和其他三种抗氧化剂——N-乙酰-L-半胱氨酸、MitoQ和MitoTEMPO对皮肤成纤维细胞的作用进行检测。成纤维细胞是皮肤真皮层中能够产生胶原蛋白的细胞,而胶原蛋白是皮肤的主要结构蛋白。

皮肤成纤维细胞来源于健康中年人、老年人以及早衰症患者——该疾病是以过快衰老为特征。

在用亚甲蓝处理成纤维细胞4周后,研究人员发现活性氧簇有所减少,而已知活性氧簇是导致皮肤细胞损伤的原因。亚甲蓝治疗还使得细胞衰老标志物减少;该化合物加速细胞分裂并减少细胞死亡。

研究小组指出,亚甲蓝比其他三种抗氧化剂更能减少皮肤成纤维细胞衰老征象。

“我们的研究表明,亚甲蓝或许是一个能够添加入护肤品使用的强大的抗氧化剂。我们看到的护肤效果不是暂时的。亚甲蓝似乎能够使皮肤细胞发生根本性的长期改变。”

“我们已开始开发含有亚甲蓝的化妆品。现在我们希望能够将它转化为上市产品。”Kan Cao教授如是说。

原始出处

Zheng-Mei Xiong, Mike O’Donovan, Linlin Sun, et al. Anti-Aging Potentials of Methylene Blue for Human Skin Longevity. Scientific Reports 7, Article number: 2475 (2017). Doi:10.1038/s41598-017-02419-3.

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    2017-06-30 微笑人参

    爱美之心不可无

    0

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    2017-06-01 cqykthl

    抗氧化剂对延缓衰老的作用

    0

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    2017-06-01 脱因不花

    哇!真好,期待有更多的成品出来

    0

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    2017-06-01 冬夜渐暖

    又了解到一种抗氧化物,很有意思

    0

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    2017-06-01 楠博One

    应该可以刮起美容旋风了

    0

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